What is GHK-Cu?
GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring copper peptide complex
found in human plasma, saliva, and urine. It plays a critical role in wound healing, tissue remodeling,
and regeneration by promoting collagen synthesis, angiogenesis, and antioxidant defense.
GHK-Cu has been studied for its applications in skin rejuvenation, hair growth, and anti-aging research.
GHK-Cu Structure
| Peptide Name | GHK-Cu |
|---|---|
| Synonyms | Copper Tripeptide-1 |
| Sequence | Gly-His-Lys + Copper (II) |
| Molecular Formula | C14H24N6O4 · Cu |
| Molecular Weight | ~403.9 g/mol (without Cu), ~405–411 g/mol (with Cu complex) |
GHK-Cu Research
1. GHK-Cu and Skin Regeneration
Studies demonstrate that GHK-Cu stimulates collagen and elastin synthesis,
accelerates wound healing, and improves skin elasticity.
It has been widely studied in cosmetic dermatology for its anti-wrinkle and rejuvenating effects.
2. GHK-Cu and Hair Growth
Research indicates that GHK-Cu promotes hair follicle enlargement and hair regrowth by
increasing blood vessel formation and stimulating dermal papilla cells.
It is a subject of research in androgenic alopecia models.
3. GHK-Cu and Anti-Inflammatory Effects
GHK-Cu has demonstrated antioxidant and anti-inflammatory properties,
helping to reduce oxidative damage and protect tissues from environmental stress.
4. GHK-Cu and Systemic Benefits
Beyond dermatology, GHK-Cu has shown potential in nerve regeneration,
organ protection, and improving tissue repair in systemic models.
Future GHK-Cu Research
Future studies are expected to explore GHK-Cu’s applications in regenerative medicine,
anti-aging therapies, and neuroprotection. Ongoing investigations also examine
its role in gene expression modulation and protective effects against chronic disease progression.
GHK-Cu Resources
- Pickart L, et al. – “GHK-Cu peptide in skin regeneration and wound healing.” J Cosmet Dermatol, 2015.
- Research on GHK-Cu in hair growth and follicle stimulation – Clin Cosmet Investig Dermatol.
- Studies on antioxidant and anti-inflammatory actions of copper peptides.

Reviews
There are no reviews yet.